Production of raspberry ketone by redirecting the metabolic flux to the phenylpropanoid pathway in tobacco plants.

ABSTRACT: Raspberry ketone is one of the characteristic flavors of raspberry fruits, and it is an important and expensive ingredient in the flavor and fragrance industries. It is present at low levels in plant tissues, and its occurrence is limited to a few taxa. In this context, the stable production of nature-identical raspberry ketone using heterologous synthesis in plants hosts has recently garnered the attention of plant biochemists. In this study, we demonstrate the rational switching of the metabolic flow from anthocyanin pigments to volatile phenylbutanoid production via the phenylpropanoid pathway. This shift led to the efficient and stable production of raspberry ketone and its glycosides via heterologous expression of the biosynthetic enzymes benzalacetone synthase (BAS) and raspberry ket

SUBMITTER: Koeduka T 

PROVIDER: S-EPMC8346687 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature