Subjective and objective screening tests for hydroxychloroquine toxicity.

ABSTRACT:

Objective

To compare subjective and objective clinical tests used in the screening for hydroxychloroquine retinal toxicity to multifocal electroretinography (mfERG) reference testing.

Design

Prospective, single-center, case control study.

Participants

Fifty-seven patients with a previous or current history of hydroxychloroquine treatment of more than 5 years' duration.

Methods

Participants were evaluated with a detailed medical history, dilated ophthalmologic examination, color fundus photography, fundus autofluorescence (FAF) imaging, spectral-domain (SD) optical coherence tomography (OCT), automated visual field testing (10-2 visual field mean deviation [VFMD]), and mfERG testing. We used mfERG test parameters as a gold standard to divide participants into 2

SUBMITTER: Cukras C 

PROVIDER: S-EPMC8356134 | biostudies-literature | 2015 Feb

REPOSITORIES: biostudies-literature