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Garland, Flower, and Petals via a Hierarchical Self-Assembly of Ursane-Type Triterpenoid Uvaol.

ABSTRACT: Uvaol, a 6-6-6-6-6 pentacyclic dihydroxy ursane-type triterpenoid, is isolable from different parts of plants Plumeria rubra, Olea europaea, Nerium oleander, Lavandula pedunculta, and Malus domestica. It is also obtained by a one-step reduction of naturally occurring triterpenoid ursolic acid. Herein, we report the first self-assembly properties of uvaol in different neat organic liquids and aqueous organic binary liquid mixtures. Spontaneous self-assembly of uvaol in different neat liquids and binary liquid mixtures yielded garland, flower, and petal-like porous superstructures of nano- to micrometer dimensions. Utilization of self-assemblies has been demonstrated in generation of anticancer drug conjugates and the removal of carcinogenic and toxic chemicals.

SUBMITTER: Ghorai S

PROVIDER: S-EPMC8359174 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature

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Garland, Flower, and Petals via a Hierarchical Self-Assembly of Ursane-Type Triterpenoid Uvaol.

Ghorai Subrata S Bag Braja Gopal BG

ACS omega 20210727 31

Uvaol, a 6-6-6-6-6 pentacyclic dihydroxy ursane-type triterpenoid, is isolable from different parts of plants Plumeria rubra, Olea europaea, Nerium oleander, Lavandula pedunculta, and Malus domestica. It is also obtained by a one-step reduction of naturally occurring triterpenoid ursolic acid. Herein, we report the first self-assembly properties of uvaol in different neat organic liquids and aqueous organic binary liquid mixtures. Spontaneous self-assembly of u ...[more]

PMID: 34396001

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