Ontology highlight
ABSTRACT:
SUBMITTER: Chen XL
PROVIDER: S-EPMC8360262 | biostudies-literature | 2021 Aug
REPOSITORIES: biostudies-literature
Chen Xiao-Lei XL Wang Jun-Hong JH Zhao Wei W Shi Chun-Wei CW Yang Kai-Dian KD Niu Tian-Ming TM Yang Gui-Lian GL Cao Xin X Jiang Yan-Long YL Wang Jian-Zhong JZ Huang Hai-Bin HB Zeng Yan Y Wang Nan N Yang Wen-Tao WT Wang Chun-Feng CF
AMB Express 20210812 1
African classical swine fever virus (ASFV) has spread seriously around the world and has dealt with a heavy blow to the pig breeding industry due to the lack of vaccines. In this study, we produced recombinant Lactobacillus plantarum (L. plantarum) expressing an ASFV p54 and porcine IL-21 (pIL-21) fusion protein and evaluated the immune effect of NC8-pSIP409-pgsA'-p54-pIL-21 in a mouse model. First, we verified that the ASFV p54 protein and p54-pIL-21 fusion protein were anchored on the surface ...[more]