Validation of the Sysmex XN-V hematology analyzer for canine specimens.

ABSTRACT:

Background

The Sysmex XN-V is derived from the new Sysmex XN series of human hematology analyzers. The main changes from the previously validated XT-2000iV analyzer include an optic-fluorescent analysis for platelets and nucleated RBC count.

Objective

We aimed to validate the Sysmex XN-V for canine blood according to American College for Veterinary Clinical Pathology and International Council for Standardization in Hematology recommendations.

Materials and methods

Canine EDTA blood specimens and quality control material were analyzed on the Sysmex XN-V to evaluate imprecision, bias, linearity, a comparison with the XT-2000iV analyzer, interference effects, carry-over, and stability. We also verified previously established Sysmex XT-2000iV reference intervals (RIs).

SUBMITTER: Grebert M 

PROVIDER: S-EPMC8362000 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature