Ontology highlight
ABSTRACT:
SUBMITTER: Siddiqui J
PROVIDER: S-EPMC8363879 | biostudies-literature | 2021 Aug
REPOSITORIES: biostudies-literature
Siddiqui Jalal J Miles Wayne O WO
Translational oncology 20210810 11
Immunotherapy has improved the prognosis for many melanoma patients; however, our capacity to predict patient responses and to understand the biological differences between patients who will or will not respond is limited. Gene expression profiling of tumors from patients who respond to immunotherapy has focused on deriving primarily immune-related signatures; however, these have shown limited predictive power. Recent studies have highlighted the role of RNA editing in modulating resistance to i ...[more]