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Conditions for metachronal coordination in arrays of model cilia.

ABSTRACT: On surfaces with many motile cilia, beats of the individual cilia coordinate to form metachronal waves. We present a theoretical framework that connects the dynamics of an individual cilium to the collective dynamics of a ciliary carpet via systematic coarse graining. We uncover the criteria that control the selection of frequency and wave vector of stable metachronal waves of the cilia and examine how they depend on the geometric and dynamical characteristics of a single cilium, as well as the geometric properties of the array. We perform agent-based numerical simulations of arrays of cilia with hydrodynamic interactions and find quantitative agreement with the predictions of the analytical framework. Our work sheds light on the question of how the collective properties of beating cilia can be determined using information about the individual units and, as such, exemplifies a bottom-up study of a rich active matter system.

SUBMITTER: Meng F

PROVIDER: S-EPMC8364176 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature

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Conditions for metachronal coordination in arrays of model cilia.

Meng Fanlong F Bennett Rachel R RR Uchida Nariya N Golestanian Ramin R

Proceedings of the National Academy of Sciences of the United States of America 20210801 32

On surfaces with many motile cilia, beats of the individual cilia coordinate to form metachronal waves. We present a theoretical framework that connects the dynamics of an individual cilium to the collective dynamics of a ciliary carpet via systematic coarse graining. We uncover the criteria that control the selection of frequency and wave vector of stable metachronal waves of the cilia and examine how they depend on the geometric and dynamical characteristics of a single cilium, as well as the ...[more]

PMID: 34362846

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