Immune checkpoint blockade in renal cell carcinoma.
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ABSTRACT:
SUBMITTER: Rappold PM
PROVIDER: S-EPMC8364550 | biostudies-literature | 2021 Mar
REPOSITORIES: biostudies-literature
Publications
Immune checkpoint blockade in renal cell carcinoma.
Rappold Phillip M PM Silagy Andrew W AW Kotecha Ritesh R RR Hakimi Ari A AA
Journal of surgical oncology 20210301 3
Immune checkpoint blockade (ICB) is the foundation of current first-line therapies in patients with metastatic renal cell carcinoma (mRCC) with the potential for eliciting long-lasting remissions. With the expanding arsenal of ICB-based therapies, biomarkers of response are urgently needed to guide optimal therapeutic selection. We review the data behind ICB therapy in RCC, emerging biomarkers of response, and the evolving role of surgery in patients with mRCC. ...[more]
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