Unknown

Dataset Information

0

The structure of a virus-encoded nucleosome.


ABSTRACT: Certain large DNA viruses, including those in the Marseilleviridae family, encode histones. Here we show that fused histone pairs Hβ-Hα and Hδ-Hγ from Marseillevirus are structurally analogous to the eukaryotic histone pairs H2B-H2A and H4-H3. These viral histones form 'forced' heterodimers, and a heterotetramer of four such heterodimers assembles DNA to form structures virtually identical to canonical eukaryotic nucleosomes.

SUBMITTER: Valencia-Sanchez MI 

PROVIDER: S-EPMC8370576 | biostudies-literature |

REPOSITORIES: biostudies-literature

Similar Datasets

2021-05-27 | PXD024220 | Pride
| S-EPMC8357426 | biostudies-literature
| S-EPMC2976404 | biostudies-literature
| S-EPMC2040038 | biostudies-literature
| S-EPMC2658732 | biostudies-literature
| S-EPMC3554055 | biostudies-literature
| S-EPMC5784010 | biostudies-literature
| S-EPMC6697550 | biostudies-literature
| S-EPMC3009600 | biostudies-literature
| S-EPMC2570626 | biostudies-literature