Ontology highlight
ABSTRACT:
SUBMITTER: Huo N
PROVIDER: S-EPMC8371129 | biostudies-literature | 2021 Aug
REPOSITORIES: biostudies-literature
Huo Nan N Cong Rui R Sun Zhi-Jia ZJ Li Wen-Chao WC Zhu Xiang X Xue Chun-Yuan CY Chen Zhao Z Ma Lu-Yuan LY Chu Zhong Z Han Yu-Chen YC Kang Xiao-Feng XF Jia Song-Hao SH Du Nan N Kang Lei L Xu Xiao-Jie XJ
Cell death & disease 20210817 9
Lactate dehydrogenase A (LDHA), a critical component of the glycolytic pathway, relates to the development of various cancers, including thyroid cancer. However, the regulatory mechanism of LDHA inhibition and the physiological significance of the LDHA inhibitors in papillary thyroid cancer (PTC) are unknown. Long non-coding RNA (lncRNA) plays a vital role in tumor growth and progression. Here, we identified a novel lncRNA LINC00671 negatively correlated with LDHA, downregulating LDHA expression ...[more]