Phase stable swept-source optical coherence tomography with active mode-locking laser for contrast enhancements of retinal angiography.

ABSTRACT: Swept-source optical coherence tomography (SS-OCT) is an attractive high-speed imaging technique for retinal angiography. However, conventional swept lasers vary the cavity length of the laser mechanically to tune the output wavelength. This causes sweep-timing jitter and hence low phase stability in OCT angiography. Here, we improve an earlier phase-stabilized, akinetic, SS-OCT angiography (OCTA) method by introducing coherent averaging. We develop an active mode-locking (AML) laser as a high phase-stable akinetic swept source for the OCTA system. The phase stability of the improved system was analyzed, and the effects of coherent averaging were validated using a retina phantom. The effectiveness of the coherent averaging method was further confirmed by comparing coherently and convention

SUBMITTER: Park KS 

PROVIDER: S-EPMC8371173 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature