Immunological parameters associated with the severity of COVID-19 pneumonia in kidney transplant recipients.

ABSTRACT:

Purpose

An outbreak of a novel respiratory disease due to coronavirus species was emerged in 2019 and named as Coronavirus Disease-2019 (COVID-19). Clinical and immunological factors affecting the course of COVID-19 in kidney transplant recipients (KTR) are not well-known.

Methods

In this prospective observational study, we presented 20 KTR with COVID-19 pnemonia and examined the factors predicting the severity of COVID-19. A total of 10 KTR without COVID-19 was used as control group. Lymphocyte subsets were determined by flow cytometry. In 13/20 patients, immunophenotyping was repeated 1 week later.

Results

Mean age of the patients was 50 ± 9 years. Patients were classified as mild-moderate (oxygen saturation: SO₂ > 90%) and severe disease groups (SO₂

SUBMITTER: Ozkok A 

PROVIDER: S-EPMC8377705 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature