Hepatitis C in healthcare personnel: follow-up analysis of treatments with direct-acting antiviral agents.

ABSTRACT:

Background

Hepatitis C infections (HCV) are associated with an increase in morbidity and mortality. The aim of this study is to update the results of treatment with direct-acting antiviral agents (DAAs) using a larger population of healthcare personnel (HP) and a longer observation period.

Methods

Secondary data analysis of DAA treatment administered to HP (with confirmed occupational acquired HCV infection) between 1 January 2014 and 30 December 2018, is based on statutory accident insurance data from Germany. The end points of the study were results of a monitoring carried out 12 and 24 weeks after the end of treatment (sustained virological response, SVR), as well as side effects and the assessment of reduced work ability after treatment. Multivariate logistic regression

SUBMITTER: Westermann C 

PROVIDER: S-EPMC8383415 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature