Neurological manifestations in COVID-19 patients and their application in predicting fatal disease: A retrospective cohort study.

ABSTRACT:

Background

To explore the development of central nervous system (CNS) symptoms and clinical application in predicting the clinical outcomes of SARS-COV-2 patients.

Methods

A retrospective cohort study was performed on the hospitalized patients with SARS-COV-2 recruited from four hospitals in Hubei Province, China from 18 January to 10 March 2020. The patients with CNS symptoms were determined. Data regarding clinical symptoms and laboratory tests were collected from medical records.

Results

Of 1268 patients studied, 162 (12.8%) had CNS symptoms, manifested as unconsciousness (71, 5.6%), coma (69, 5.4%), dysphoria (50, 3.9%), somnolence (34, 2.7%) and convulsion (3, 0.2%), which were observed at median of 14 (interquartile range 9-18) days after symptom onset and signi

SUBMITTER: Zhao TS 

PROVIDER: S-EPMC8384758 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature