Social integration and inflammation in individuals with and without posttraumatic stress disorder.

ABSTRACT:

Background

Posttraumatic stress disorder (PTSD) is associated with increased risk for morbidity and mortality, which may be mediated through elevated inflammation. In contrast, social support appears to protect against morbidity and mortality, reduce levels of inflammation, and improve PTSD outcomes.

Methods

We examined relationships among social isolation, perceived social support, and inflammation in Veterans Affairs (VA) patients with and without PTSD. Our sample included 735 (35% PTSD+) participants from the Mind Your Heart Study (mean age = 58 ± 11; 94% male). Social isolation was assessed with the Berkman Syme Social Network Index; perceived social support with the Multidimensional Scale of Perceived Social Support; and PTSD with the Clinician Administered PTSD Scale.

SUBMITTER: Ahmadian AJ 

PROVIDER: S-EPMC8388310 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature