TRIM22. A Multitasking Antiviral Factor.
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ABSTRACT:
SUBMITTER: Pagani I
PROVIDER: S-EPMC8391480 | biostudies-literature | 2021 Jul
REPOSITORIES: biostudies-literature
Publications
TRIM22. A Multitasking Antiviral Factor.
Pagani Isabel I Poli Guido G Vicenzi Elisa E
Cells 20210723 8
Viral invasion of target cells triggers an immediate intracellular host defense system aimed at preventing further propagation of the virus. Viral genomes or early products of viral replication are sensed by a number of pattern recognition receptors, leading to the synthesis and production of type I interferons (IFNs) that, in turn, activate a cascade of IFN-stimulated genes (ISGs) with antiviral functions. Among these, several members of the tripartite motif (TRIM) family are antiviral executor ...[more]
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