Acute micro-thrombosis after subarachnoid hemorrhage: A new therapeutic target?
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ABSTRACT:
SUBMITTER: Ye F
PROVIDER: S-EPMC8393286 | biostudies-literature | 2021 Sep
REPOSITORIES: biostudies-literature
Publications
Acute micro-thrombosis after subarachnoid hemorrhage: A new therapeutic target?
Ye Fenghui F Keep Richard F RF Hua Ya Y Garton Hugh Jl HJ Xi Guohua G
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20210517 9
Microthrombi formation in the brain following subarachnoid hemorrhage (SAH) has been recognized and suspected to contribute to cerebral ischemia. A recent study found that ultra-early cerebral micro-thrombosis occured four hours after experimental SAH. The number of thrombotic microvessels correlated with brain-blood barrier disruption and neuronal injury. If acute cerebral micro-thrombi also occur in humans, is it time to develop a therapy with systemic thrombolysis for SAH patients? ...[more]
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