Umbilical artery lactate levels and associated maternal and newborn characteristics at Mulago National Referral Hospital: a cross-sectional observational study.
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ABSTRACT: Objective
To determine the maternal and newborn characteristics associated with high umbilical artery lactate levels at Mulago National Referral Hospital.Design
Cross-sectional observational study.Setting
Department of Obstetrics and Gynecology at a national referral hospital located in the capital of Uganda, Kampala.Participants
We randomly selected 720 pregnant mothers at term who presented in labour and their newborn babies.Primary outcome
Umbilical artery lactate level.Results
During the study, there were 579 vaginal deliveries (18 instrumental) and 141 caesarean sections which met the inclusion criteria. One hundred and eighty-seven neonates (187) had high arterial lactate levels. The following factors were associated with an increased likelihood of high lactate concentration: male sex (adjusted OR (aOR)=1.71; 95% CI 1.16 to 2.54; p<0.05), primigravidity (aOR=2.78; 95% CI 1.89 to 4.08; p<0.001), meconium-stained liquor (aOR=5.85; 95% CI 4.08 to 8.47; p<0.001) and administration of oxytocin (aOR=1.97; 95% CI 1.00 to 3.77; p<0.05).Conclusion
About a fifth of the babies born in Mulago National Referral Hospital during the study period had high umbilical artery lactate. The maternal-fetal factors significantly associated with high umbilical artery lactate levels included: baby's sex, mother's gravidity, meconium-stained amniotic fluid and oxytocin administration during labour.
SUBMITTER: Ogik V
PROVIDER: S-EPMC8395270 | biostudies-literature |
REPOSITORIES: biostudies-literature
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