The D-dimer level predicts the prognosis in patients with lung cancer: a systematic review and meta-analysis.

ABSTRACT:

Objective

Although the significance of increased plasma D-dimer levels in activating coagulation and fibrinolysis has been reported, it is still controversial whether it can be used to predict the prognosis of lung cancer patients. This meta-analysis was performed to explore the beneficial role of plasma D-dimer as a prognostic factor in lung cancer patients according to a larger sample capacity.

Materials and methods

MEDLINE, EMBASE, and Cochrane Central databases were searched from inception to January 2021. The data are mainly hazard ratio(HR) with 95% confidence interval (CI) and Kaplan-Meier survival curves. The publication bias was examined by Egger's test.

Results

Finally, a total of 28 studies, enrolling 8452 patients were included in the current meta-analysis

SUBMITTER: Ma M 

PROVIDER: S-EPMC8399789 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature