Healthy Oral Lifestyle Behaviours Are Associated with Favourable Composition and Function of the Oral Microbiota.

ABSTRACT: Modifiable lifestyle interventions may influence dental disease by shifting the composition of the oral microbiota. This study aimed to test whether lifestyle traits are associated with oral microbiota composition and function. Swedish volunteers, aged 16 to 79 years, completed a lifestyle traits questionnaire including lifestyle characteristics and oral health behaviours. Bacterial 16S rDNA amplicons were sequenced and classified into genera and species, using salivary DNA. Microbiota functions were predicted using Phylogenetic Investigation of Communities by Reconstruction of Unobserved States and the KO Database of Molecular Functions by ortholog annotation. Tests for association used partial least squares and linear regression analysis with correction for multiple testing. The main ana

SUBMITTER: Hallang S 

PROVIDER: S-EPMC8401320 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature