Plasmodium vivax Genetic Diversity in Panama: Challenges for Malaria Elimination in Mesoamerica.

ABSTRACT: Panama and all nations within the Mesoamerican region have committed to eliminate malaria within this decade. With more than 90% of the malaria cases in this region caused by Plasmodium vivax, an efficient national/regional elimination plan must include a comprehensive study of this parasite's genetic diversity. Here, we retrospectively analyzed P. vivax genetic diversity in autochthonous and imported field isolates collected in different endemic regions in Panama from 2007 to 2020, using highly polymorphic markers (csp, msp-1, and msp-3α). We did the analysis using molecular techniques that are cost-effective for malaria molecular surveillance within Mesoamerica. Thus, we used molecular analyses that are feasible for malaria molecular surveillance within

SUBMITTER: Santamaria AM 

PROVIDER: S-EPMC8401434 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature