Ontology highlight
ABSTRACT:
SUBMITTER: Maruyama K
PROVIDER: S-EPMC8403767 | biostudies-literature | 2021 Sep
REPOSITORIES: biostudies-literature
Maruyama Kazuaki K Naemura Kazuaki K Yoshihara Kenji K Imanaka-Yoshida Kyoko K Kurihara Hiroki H Miyagawa-Tomita Sachiko S
STAR protocols 20210826 3
Myocardial infarction (MI) is one of the most common causes of death worldwide. Animal models for MI are useful for studying the pathophysiology and developing therapies. Here, we describe a surgical protocol for permanent ligation of the left anterior descending coronary artery in mice, which mimics human acute coronary syndrome. This protocol includes descriptive step-by-step surgical procedures and high-quality surgical videos, which are useful for performing stable and highly reproducible op ...[more]