Age-related radiomorphometric changes on panoramic radiographs.
Ontology highlight
ABSTRACT: Objectives
We aimed to analyse age-related anatomical changes in teeth and mandibular structures using panoramic radiographs.Materials and methods
We included 471 subjects aged 13-70 years (mean, 35.12 ± 18.72 years). Panoramic radiographs were used to record intraoral condition and radiomorphometric parameters. After grouping the subjects by age decade, descriptive statistics and analysis of variance were performed to assess age-related patterns.Results
The number of missing teeth, endodontically treated teeth, full veneer crowns, and implant prosthesis increased with age (all p < .05). The prevalence of periodontitis significantly increased after the 40s and was the highest in the 60s (57.1%). The maxillary canine root was the longest in the 10s and 20s (p < .001). With age, the mandibular canal and mental foramen moved towards the alveolar bone crest, on the opposite side of the mandibular inferior border. The pulp area and pulp-to-tooth ratio of maxillary/mandibular first molars were significantly higher in the 10s and 20s than in other age groups (all p < .05).Conclusions
We provided comprehensive information on age-related anatomical changes in teeth and mandibular structures based on panoramic radiographs. Various radiographic parameters showed specific changes with increasing age. Assessing these age-related changes can be useful in determining an individual's age, and may aid in medico-legal and forensic judgments.
SUBMITTER: Lee YH
PROVIDER: S-EPMC8404498 | biostudies-literature |
REPOSITORIES: biostudies-literature
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Project description:Hui2014 - Age-related changes in articular
cartilage
This model is described in the article:
Oxidative changes and
signalling pathways are pivotal in initiating age-related
changes in articular cartilage
Wang Hui1, David A Young1, Andrew D
Rowan1, Xin Xu2, Tim E Cawston1, Carole J Proctor1,3
Annals of the Rheumatic Diseases
Abstract:
Objective: To use a computational approach to investigate
the cellular and extracellular matrix changes that occur with
age in the knee joints of mice. Methods: Knee joints from an
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metalloproteinase-13 (MMP-13), nitrotyrosine, LC-3B, Bcl-2, and
cleaved type II collagen used for immunohistochemistry. Based
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and anaplastic lymphoma kinase (ALK1) staining in cartilage
increased with age with a concomitant decrease in LC-3B and
Bcl-2. Stochastic simulations from the computational model
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growth factor-? signalling via ALK1/ALK5 receptors was
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cartilage matrix and cellularity occurs with age. This is
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apoptosis and MMP-13 and a decrease in chondrocyte autophagy.
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develop osteoarthritis with age. Computational modelling
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involved in age-related changes in musculoskeletal tissues.
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2024-09-02 | BIOMD0000000560 | BioModels
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