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The BNT162b2 mRNA Vaccine Elicits Robust Humoral and Cellular Immune Responses in People Living With Human Immunodeficiency Virus (HIV).


ABSTRACT: Previous studies have shown that certain vaccines induce suboptimal responses in people living with human immunodeficiency virus (HIV, PLWH). However, responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines have not been fully characterized in these patients. Here we show that the BNT162b2 vaccine induces robust immune responses comparable to responses in healthy donors.

SUBMITTER: Woldemeskel BA 

PROVIDER: S-EPMC8406881 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature

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The BNT162b2 mRNA Vaccine Elicits Robust Humoral and Cellular Immune Responses in People Living With Human Immunodeficiency Virus (HIV).

Woldemeskel Bezawit A BA   Karaba Andrew H AH   Garliss Caroline C CC   Beck Evan J EJ   Wang Kristy H KH   Laeyendecker Oliver O   Cox Andrea L AL   Blankson Joel N JN  

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20220401 7


Previous studies have shown that certain vaccines induce suboptimal responses in people living with human immunodeficiency virus (HIV, PLWH). However, responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines have not been fully characterized in these patients. Here we show that the BNT162b2 vaccine induces robust immune responses comparable to responses in healthy donors. ...[more]

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