Validation of the Clinical Assessment Scale for Autoimmune Encephalitis: A Multicenter Study.

ABSTRACT:

Introduction

A new scale, named the Clinical Assessment Scale for Autoimmune Encephalitis (CASE), has recently been developed for rating the severity of autoimmune encephalitis (AE) with a high level of clinimetric properties. In this study, our primary objective was to validate the performance of CASE through a multicenter study in China.

Methods

Between July 2014 and December 2019, 143 consecutive patients with definite neuronal surface antibody-associated AE from three tertiary hospitals were enrolled in the study. We validated the reliability, internal consistency, and validity of CASE. We further compared CASE with the modified Rankin scale (mRS) among different subtypes of AE in terms of its sensitivity to disease dynamics. Statistical analyses were performed using Gra

SUBMITTER: Cai MT 

PROVIDER: S-EPMC8412851 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature