The correlation between serum selenium, zinc, and COVID-19 severity: an observational study.

ABSTRACT:

Background

Without an adequate immune response, SARS-CoV2 virus can simply spread throughout the body of the host. Two of the well-known immunonutrients are selenium (Se) and zinc (Zn). Se and Zn deficiency might lead to inflammation, oxidative stress, and viral entry into the cells by decreasing ACE-2 expression; three factors that are proposed to be involved in COVID-19 pathogenesis. Thus, in the current study we aimed at evaluating the correlation between serum Se and Zn status and COVID-19 severity.

Methods

Eighty-four COVID-19 patients were enrolled in this observational study. Patients were diagnosed based on an infectious disease specialist diagnosis, using WHO interim guidance and the recommendations of the Iranian National Committee of Covid-19. The patients with ac

SUBMITTER: Razeghi Jahromi S 

PROVIDER: S-EPMC8414458 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature