Project description:Facioscapulohumeral muscular dystrophy (FSHD) is the second most common genetic myopathy, characterized by slowly progressing and highly heterogeneous muscle wasting with a typical onset in the late teens/early adulthood [1]. Although the etiology of the disease for both FSHD type 1 and type 2 has been attributed to gain-of-toxic function stemming from aberrant DUX4 expression, the exact pathogenic mechanisms involved in muscle wasting have yet to be elucidated [2-4]. The 2021 FSHD International Research Congress, held virtually on June 24-25, convened over 350 researchers and clinicians to share the most recent advances in the understanding of the disease mechanism, discuss the proliferation of interventional strategies and refinement of clinical outcome measures, including results from the ReDUX4 trial, a phase 2b clinical trial of losmapimod in FSHD [NCT04003974].

| S-EPMC8762812 | biostudies-literature

Proceedings of Reanimation 2021, the French Intensive Care Society International Congress.

Project description: Not available

| S-EPMC8239334 | biostudies-literature

Abstracts of the XIX International Congress of Neuropathology, Tokyo, Japan, September 23-27, 2018.

Project description: Not available

| S-EPMC8028628 | biostudies-literature

ISPN 2021 Virtual Meeting of the International Society for Pediatric Neurosurgery : Virtual Meeting, 5 - 7 November 2021.

Project description: Not available

| S-EPMC8556790 | biostudies-literature

43rd Annual Meeting of the European Thyroid Association. Virtual Conference, September 4–7, 2021

Project description: Not available