Project description:We here find that Lkb1-deficient lung tumors from KL model harbor stronger stemness and show the upregulation of Nanog expression in contrast to KrasG12D/+ or KrasG12D/+; P53-/- tumors.

| OEX002292 | NODE

Gemcitabine and Chk1 Inhibitor AZD7762 Synergistically Suppress the Growth of Lkb1-Deficient Lung Adenocarcinoma.

Project description: Not available

| S-EPMC5600859 | biostudies-literature

Two-stage induced differentiation of OCT4+/Nanog+ stem-like cells in lung adenocarcinoma.

Project description: Not available

| S-EPMC5356561 | biostudies-literature

Gli1 regulates stemness characteristics in gastric adenocarcinoma.

Project description: Not available

| S-EPMC7236965 | biostudies-literature

The deubiquitinase USP21 maintains the stemness of mouse embryonic stem cells via stabilization of Nanog.

Project description: Not available

| S-EPMC5133637 | biostudies-literature

Nkx2-1 represses a latent gastric differentiation program in lung adenocarcinoma.

Project description: Not available

| S-EPMC3721642 | biostudies-literature

LKB1 modulates lung cancer differentiation and metastasis

Project description: Not available

| S-ECPF-GEOD-6135 | biostudies-other

CENPA regulates tumor stemness in lung adenocarcinoma.

Project description: Not available

| S-EPMC9320546 | biostudies-literature

Dataset Information

Nanog maintains stemness of Lkb1-deficient lung adenocarcinoma and prevents gastric differentiation.

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