Impact of insulin therapy on the mortality of acute heart failure patients with diabetes mellitus.

ABSTRACT:

Background

Patients with diabetes mellitus (DM) have a higher prevalence of heart failure (HF) than those without it. Approximately 40 % of HF patients have DM and they tend to have poorer outcomes than those without DM. This study evaluated the impact of insulin therapy on mortality among acute HF patients.

Methods

A total of 1740 patients from the Korean Acute Heart Failure registry with DM were included in this study. The risk of all-cause mortality according to insulin therapy was assessed using the Cox proportional hazard models with inverse probability of treatment weighting to balance the clinical characteristics (pretreatment covariates) between the groups.

Results

DM patients had been treated with either oral hypoglycemic agents (OHAs) alone (n = 620), insuli

SUBMITTER: Jang SY 

PROVIDER: S-EPMC8424885 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature