Ontology highlight
ABSTRACT:
SUBMITTER: Hu M
PROVIDER: S-EPMC8428972 | biostudies-literature | 2021
REPOSITORIES: biostudies-literature
Hu Min M Rogers Natasha M NM Li Jennifer J Zhang Geoff Y GY Wang Yuan Min YM Shaw Karli K O'Connell Philip J PJ Alexander Stephen I SI
Frontiers in immunology 20210826
Kidney transplantation is the most common solid organ transplant and the best current therapy for end-stage kidney failure. However, with standard immunosuppression, most transplants develop chronic dysfunction or fail, much of which is due to chronic immune injury. Tregs are a subset of T cells involved in limiting immune activation and preventing autoimmune disease. These cells offer the potential to provide tolerance or to allow reduction in immunosuppression in kidney transplants. The import ...[more]