Spatial inequality through the prism of a pandemic: Covid-19 in South Africa.
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ABSTRACT:
SUBMITTER: Shifa M
PROVIDER: S-EPMC8435065 | biostudies-literature |
REPOSITORIES: biostudies-literature
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Project description:BackgroundGiven the economic and social divide that exists in South Africa, it is critical to manage the health response of its residents to the Covid-19 pandemic within the different socio-economic contexts that define the lived realities of individuals.ObjectiveThe objective of this study is to analyse the Covid-19 preventive behaviour and the socio-economic drivers behind the health-response behaviour.DataThe study employs data from waves 1 and 2 of South Africa's nationally representative National Income Dynamics Study (NIDS)-Coronavirus Rapid Mobile Survey (CRAM). The nationally representative panel data has a sample of 7073 individuals in Wave 1 and 5676 individuals in Wave 2.MethodsThe study uses bivariate statistics, concentration indices and multivariate estimation techniques, ranging from a probit, control-function approach, special-regressor method and seemingly unrelated regression to account for endogeneity while identifying the drivers of the response behaviour.FindingsThe findings indicate enhanced behavioural responsiveness to Covid-19. Preventive behaviour is evolving over time; the use of face mask has overtaken handwashing as the most utilised preventive measure. Other measures, like social distancing, avoiding close contact, avoiding big groups and staying at home, have declined between the two periods of the study. There is increased risk perception with significant concentration among the higher income groups, the educated and older respondents. Our findings validate the health-belief model, with perceived risk, self-efficacy, perceived awareness and barriers to preventive strategy adoption identified as significant drivers of health-response behaviour. Measures such as social distancing, avoiding close contact, and the use of sanitisers are practised more by the rich and educated, but not by the low-income respondents.ConclusionThe respondents from lower socio-economic backgrounds are associated with optimism bias and face barriers to the adoption of preventive strategies. This requires targeted policy attention in order to make response behaviour effective.
| S-EPMC8051761 | biostudies-literature
Project description:Since its emergence late in 2019, the COVID-19 pandemic continues to exude major public health and socio-economic burden globally. South Africa is currently the epicenter for the pandemic in Africa. This study is based on the use of a compartmental model to analyze the transmission dynamics of the disease in South Africa. A notable feature of the model is the incorporation of the role of environmental contamination by COVID-infected individuals. The model, which is fitted and parametrized using cumulative mortality data from South Africa, is used to assess the impact of various control and mitigation strategies. Rigorous analysis of the model reveals that its associated continuum of disease-free equilibria is globally-asymptotically stable whenever the control reproduction number is less than unity. The epidemiological implication of this result is that the disease will eventually die out, particularly if control measures are implemented early and for a sustainable period of time. For instance, numerical simulations suggest that if the lockdown measures in South Africa were implemented a week later than the 26 March, 2020 date it was implemented, this will result in the extension of the predicted peak time of the pandemic, and causing about 10% more cumulative deaths. In addition to illustrating the effectiveness of self-isolation in reducing the number of cases, our study emphasizes the importance of surveillance testing and contact tracing of the contacts and confirmed cases in curtailing the pandemic in South Africa.
| S-EPMC7402282 | biostudies-literature
Project description:There is a growing concern that inequalities are hindering health outcomes. This paper's primary objective is to investigate the role of relative deprivation and inequality in explaining the daily spread of the Covid-19 pandemic. For this purpose, we use secondary cross-sectional data across 119 (developed and developing) countries from January 2020 - to April 2021. For the empirical analysis, we use a recent dynamic panel data modelling approach that allows us to identify the role of time-invariant variables such as degree of globalisation, political freedom and income inequality on the dynamics of the pandemic and fatality rates across countries. We find that new cases per million and fatality rates are highly persistent processes. After controlling for time-varying mobility statistics from the Google mobility database and region-specific dummy variables, the two significant factors that explain the severity of Covid-19 spread in a country are per-capita Gross Domestic Product (GDP) and Yitzhaki's relative income deprivation index. Lagged value of new cases per million significantly explains cross-country variations in the daily case fatality rates. A higher proportion of the older population and pollution increased fatality rates while better medical infrastructure reduced it.
| S-EPMC10027304 | biostudies-literature
Project description:BackgroundThe devastating health and economic impact of the COVID-19 pandemic led to a global response in the development of effective vaccines to fight the disease in an extraordinarily short time. Both the development and the production of these vaccines opened a path of hope, but the inequality in vaccine distribution raises great concerns about the possibility of effectively eradicating the virus.MethodsIt is particularly important to analyse the extent to which vaccines are equally distributed and investigate the possible effects of vaccine inequalities as well as its major drivers. For this purpose, this paper investigates the extent of equitable vaccine distribution using some well-known inequality measures and disentangles the main drivers of the share of vaccination. In addition, the paper analyses the relationship between the vaccination rate, the GDP growth, and the incidence of the coronavirus disease, with the aim of providing empirical evidence on existing relationships worldwide.ResultsOur findings show that the situation is more challenging in less developed countries, especially African countries, due to weak health systems and low rates of vaccination. Moreover, we find a positive relationship between the share of vaccinated individuals and GDP. Consequently, the poorest, least developed countries with a lower rate of vaccine uptake will experience lower GDP growth.ConclusionsVaccines and the vaccination process reveal the existing inequalities between countries and how they, in turn, impact the well-being of their citizens. People who live in less developed countries have a lower probability of being vaccinated, which translates into a greater probability of dying from COVID. Countries are seeing their economic future compromised by low vaccination levels, given the positive and significant relationship between the vaccination rate and GDP growth. In short, while some countries are trying to get back to some sort of normality, even with some pandemic protocols, the situation in less developed countries is more challenging due to weak health systems and low rates of vaccination. Consequently, the poorest, least developed countries with a lower rate of vaccine penetration will experience lower GDP growth, and the pandemic will have a greater effect on their economy due to low vaccination rates.
| S-EPMC9126303 | biostudies-literature
Project description:Covalent modification cycles are basic units and building blocks of posttranslational modification and cellular signal transduction. We systematically explore different spatial aspects of signal transduction in covalent modification cycles by starting with a basic temporal cycle as a reference and focusing on steady-state signal transduction. We consider, in turn, the effect of diffusion on spatial signal transduction, spatial analogs of ultrasensitive behavior, and the interplay between enzyme localization and substrate diffusion. Our analysis reveals the need to explicitly account for kinetics and diffusional transport (and localization) of enzymes, substrates, and complexes. It demonstrates a complex and subtle interplay between spatial heterogeneity, diffusion, and localization. Overall, examining the spatial dimension of covalent modification reveals that 1), there are important differences between spatial and temporal signal transduction even in this cycle; and 2), spatial aspects may play a substantial role in affecting and distorting information transfer in modules/networks that are usually studied in purely temporal terms. This has important implications for the systematic understanding of signaling in covalent modification cycles, pathways, and networks in multiple cellular contexts.
| S-EPMC3822675 | biostudies-other
Project description:An estimated 2 million foreign-born migrants of working age (15-64) were living in South Africa (SA) in 2017. Structural and practical xenophobia has driven asylum-seekers, refugees, and undocumented migrants in SA to abject poverty and misery. The Coronavirus Disease 2019 (COVID-19) containment measures adopted by the SA government through the lockdown of the nation have tremendously deepened the unequal treatment of asylum-seekers and refugees in SA. This can be seen through the South African government's lack of consideration of this marginalized population in economic, poverty, and hunger alleviation schemes. Leaving this category of our society out of the national response safety nets may lead to negative coping strategies causing mental health issues and secondary health concerns. An effective response to the socioeconomic challenges imposed by the COVID-19 pandemic should consider the economic and health impact of the pandemic on asylum-seekers, refugees, and undocumented migrants.
| S-EPMC7439241 | biostudies-literature
Project description:Objective: We explore gender differences in mental health deterioration and psychological well-being due to the COVID-19 pandemic, as well as the mechanisms through which these differences may operate. Methods: Using data from the Life during Pandemic survey in Chile, which covers 2,545 adult respondents, we estimate econometric models to explore gender differences in psychological well-being and mental health as well as economic fragility and household workload during the COVID-19 pandemic. Results: We find women are more likely to report overall bad mental health and deterioration of well-being. They are also more likely to have a new diagnosis of a mental health problem, to be pursuing treatment and taking prescription medication. Moreover, women report an increase in household chores and in childcare, and are more likely to have lost their employment or experienced a loss of income due to the pandemic. Conclusion: Our results offer a general picture of gender differences in the psychological impact of COVID-19. We argue that policies that mitigate economic stress and address the needs of women specifically may ease mental health deterioration due to the pandemic.
| S-EPMC8698135 | biostudies-literature
Project description:ObjectiveThe purpose of this study was to assess the self-reported depression, anxiety, and stress responses of chiropractors in South Africa during the first year of the COVID-19 pandemic.MethodsThis was an explorative cross-sectional survey. The survey was distributed to 884 chiropractors through the membership databases of the Chiropractic Association of South Africa and the Allied Health Professions Council of South Africa from July 9, 2020, until August 4, 2020. The study was conducted through Google Forms and included the Depression, Anxiety, and Stress Scale questionnaire. Data were analyzed using the Kolmogorov-Smirnov and Shapiro-Wilk tests and comparatively using the Mann-Whitney U and Kruskal-Wallis tests.ResultsThe response rate was 17%. The chiropractor scores for depression, anxiety, and stress were within the normal range (7.35, 5.42, and 11.58, respectively). Female chiropractors under the age of 40 years old were found to be affected to a greater degree than the other participants in this study (9.87, 7.56, and 14.14).ConclusionSelf-reported levels for stress, anxiety, and depression among chiropractors in South Africa were found to be within normal limits during the initial phase of the COVID-19 pandemic.
| S-EPMC9526351 | biostudies-literature
Project description: Not available
| S-BSST1055 | biostudies-other
Project description:BackgroundThe linkage between the socio-economic inequality and HIV outcomes was analysed using data from a population-based household survey that employed multistage-stratified sampling. The goal is to help refocus attention on how HIV is linked to inequalities.MethodsA socio-economic index (SEI) score, derived using Multiple Correspondence Analysis of measures of ownership of durable assets, was used to generate three SEI groups: Low (poorest), Middle, and Upper (no so poor). Distribution of HIV outcomes (i.e. HIV prevalence, access to HIV/AIDS information, level of stigma towards HIV/AIDS, perceived HIV risk and sexual behaviour) across the SEI groups, and other background characteristics was assessed using weighted data. Univariate and multivariate logistic regression was used to assess the covariates of the HIV outcomes across the socio-economic groups. The study sample include 14,384 adults 15 years and older.ResultsMore women (57.5%) than men (42.3%) were found in the poor SEI [P<0.001]. HIV prevalence was highest among the poor (20.8%) followed by those in the middle (15.9%) and those in the upper SEI (4.6%) [P<0.001]. It was also highest among women compared to men (19.7% versus 11.4% respectively) and among black Africans (20.2%) compared to other races [P<0.001]. Individuals in the upper SEI reported higher frequency of HIV testing (59.3%) compared to the low SEI (47.7%) [P< 0.001]. Only 20.5% of those in poor SEI had "good access to HIV/AIDS information" compared to 79.5% in the upper SEI (P<0.001). A higher percentage of the poor had a stigmatizing attitude towards HIV/AIDS (45.6%) compared to those in the upper SEI (34.8%) [P< 0.001]. There was a high personal HIV risk perception among the poor (40.0%) and it declined significantly to 10.9% in the upper SEI.ConclusionsOur findings underline the disproportionate burden of HIV disease and HIV fear among the poor and vulnerable in South Africa. The poor are further disadvantaged by lack of access to HIV information and HIV/AIDS services such as testing for HIV infection. There is a compelling urgency for the national HIV/AIDS response to maximizing program focus for the poor particularly women.
| S-EPMC4228412 | biostudies-literature