Dataset Information

The Korean Hypertension Cohort study: design and baseline characteristics.

ABSTRACT:

Background/aims

Hypertension (HT) has a significant impact on public health and medical expenses. However, HT is a chronic disease that requires the long-term follow-up of a large number of patients.

Methods

The Korean Hypertension Cohort (KHC) study aimed to develop a model for calculating cardiovascular risk in HT patients by linking and utilizing the detailed clinical and longitudinal data from hospitals and the national health insurance claim database, respectively. This cohort had a planned sample size of over 11,000 HT patients and 100,000 non-HT controls. Eligible patients were hypertensive patients, who were presenting for the first time and were diagnosed with HT as a main disease from 2006 to 2011. Long-term survival data over a period of approximately 9 years were obtained from the national health insurance claim and national health examination data.

Results

This cohort enrolled 11,083 patients with HT. The mean age was 58.87 ± 11.5 years, 50.5% were male, and 31.4% were never-treated HT. Of the enrolled patients, 32.9% and 37.7% belonged to the high and moderate cardiovascular risk groups, respectively. Initial blood pressures were 149.4 ± 18.5/88.5 ± 12.5 mmHg. During the 2 years hospital data follow-up period, blood pressures lowered to 130.8 ± 14.1/78.0 ± 9.7 mmHg with 1.9 ± 1.0 tablet doses of antihypertensive medication. Cardiovascular events occurred in 7.5% of the overall patients; 8.5%, 8.8%, and 4.7% in the high, moderate, and low risk patients, respectively.

Conclusion

The KHC study has provided important information on the long-term outcomes of HT patients according to the blood pressure, comorbid diseases, medication, and adherence, as well as health behaviors and health resource use.

SUBMITTER: Lee HY

PROVIDER: S-EPMC8435490 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature

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Publications

The Korean Hypertension Cohort study: design and baseline characteristics.

Lee Hae-Young HY Lee Ju-Yeon JY Shin Ho-Gyun HG Cho Song-Hee SH Park Kyun-Ik KI Oh Gyu-Chul GC Lee Seung-Pyo SP Kim Hogon H Lee Hee-Sun HS Kim Kwang-Il KI Kang Si-Hyuck SH Lee Jang Hoon JH Jang Se Yong SY Lee Ju-Hee JH Kim Kye Hun KH Cho Jae Yeong JY Park Jae-Hyeong JH Jang Jieun J Park Sue K SK Bak Jean Kyung JK

The Korean journal of internal medicine 20210722 5

<h4>Background/aims</h4>Hypertension (HT) has a significant impact on public health and medical expenses. However, HT is a chronic disease that requires the long-term follow-up of a large number of patients.<h4>Methods</h4>The Korean Hypertension Cohort (KHC) study aimed to develop a model for calculating cardiovascular risk in HT patients by linking and utilizing the detailed clinical and longitudinal data from hospitals and the national health insurance claim database, respectively. This cohor ...[more]

PMID: 34289586

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Dataset Information

The Korean Hypertension Cohort study: design and baseline characteristics.

Background/aims

Methods

Results

Conclusion

Publications

The Korean Hypertension Cohort study: design and baseline characteristics.

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