How Will Genetics Inform the Clinical Care of Atrial Fibrillation?

ABSTRACT: Susceptibility to atrial fibrillation (AF) is determined by well-recognized risk factors such as diabetes mellitus or hypertension, emerging risk factors such as sleep apnea or inflammation, and increasingly well-defined genetic variants. As discussed in detail in a companion article in this series, studies in families and in large populations have identified multiple genetic loci, specific genes, and specific variants increasing susceptibility to AF. Since it is becoming increasingly inexpensive to obtain genotype data and indeed whole genome sequence data, the question then becomes to define whether using emerging new genetics knowledge can improve care for patients both before and after development of AF. Examples of improvements in care could include identifying patients at increased r

SUBMITTER: Shoemaker MB 

PROVIDER: S-EPMC8436048 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature