Ontology highlight
ABSTRACT:
SUBMITTER: Carreras-Badosa G
PROVIDER: S-EPMC8440501 | biostudies-literature | 2021 Sep
REPOSITORIES: biostudies-literature
Carreras-Badosa Gemma G Gómez-Vilarrubla Ariadna A Mas-Parés Berta B Xargay-Torrent Silvia S Prats-Puig Anna A Puerto-Carranza Elsa E de Zegher Francis F Ibáñez Lourdes L Bassols Judit J López-Bermejo Abel A
Scientific reports 20210914 1
Both the innate and adaptive immune responses are deregulated in individuals with obesity and are key drivers of its associated metabolic alterations. Although the anti-inflammatory growth differentiation factor 15 (GDF-15) is a candidate protein against obesity, its mechanisms regulating the immune responses are not fully cleared. We examined whether GDF-15 was related to serum immunoglobulins in a children's cohort assessed longitudinally during childhood. Results showed that circulating GDF-1 ...[more]