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Trimacrocyclic hexasubstituted benzene linked by labile octahedral [X(CHCl₃)₆]^- clusters.

ABSTRACT: Crystalline supramolecular architectures mediated by cations, anions, ion pairs or neutral guest species are well established. However, the robust crystallization of a well-designed receptor mediated by labile anionic solvate clusters remains unexplored. Herein, we describe the synthesis and crystalline behaviors of a trimacrocyclic hexasubstituted benzene 2 in the presence of guanidium halide salts and chloroform. Halide hexasolvate clusters, viz. [Cl(CHCl₃)₆]^-, [Br(CHCl₃)₆]^-, and [I(CHCl₃)₆]^-, were found to be critical to the crystallization process, as suggested by the single-crystal structures, X-ray powder diffraction (XRPD), thermogravimetric analysis (TGA), scanning electron microscopy with energy dispersive spectroscopy (SEM-EDS), and NMR spectroscopy. This study demonstrates the hitherto unexpected role that labile ionic solvate clusters can play in stabilizing supramolecular architectures.

SUBMITTER: Lai Z

PROVIDER: S-EPMC8442620 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature

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Trimacrocyclic hexasubstituted benzene linked by labile octahedral [X(CHCl3)6]- clusters.

Lai Zhenzhen Z Li Aimin A Peng Sangshan S Sessler Jonathan L JL He Qing Q

Chemical science 20210812 35

Crystalline supramolecular architectures mediated by cations, anions, ion pairs or neutral guest species are well established. However, the robust crystallization of a well-designed receptor mediated by labile anionic solvate clusters remains unexplored. Herein, we describe the synthesis and crystalline behaviors of a trimacrocyclic hexasubstituted benzene 2 in the presence of guanidium halide salts and chloroform. Halide hexasolvate clusters, viz. [Cl(CHCl3)6 ...[more]

PMID: 34659699

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