The prevalence and density of asymptomatic Plasmodium falciparum infections among children and adults in three communities of western Kenya.

ABSTRACT:

Background

Further reductions in malaria incidence as more countries approach malaria elimination require the identification and treatment of asymptomatic individuals who carry mosquito-infective Plasmodium gametocytes that are responsible for furthering malaria transmission. Assessing the relationship between total parasitaemia and gametocytaemia in field surveys can provide insight as to whether detection of low-density, asymptomatic Plasmodium falciparum infections with sensitive molecular methods can adequately detect the majority of infected individuals who are potentially capable of onward transmission.

Methods

In a cross-sectional survey of 1354 healthy children and adults in three communities in western Kenya across a gradient of malaria transmission (Ajigo, Webuye,

SUBMITTER: Salgado C 

PROVIDER: S-EPMC8447531 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature