Ontology highlight
ABSTRACT:
SUBMITTER: Bartels K
PROVIDER: S-EPMC8453700 | biostudies-literature | 2021 Sep
REPOSITORIES: biostudies-literature
Bartels Kim K Lasitza-Male Tanya T Hofmann Hagen H Löw Christian C
Chembiochem : a European journal of chemical biology 20210521 17
Uncovering the structure and function of biomolecules is a fundamental goal in structural biology. Membrane-embedded transport proteins are ubiquitous in all kingdoms of life. Despite structural flexibility, their mechanisms are typically studied by ensemble biochemical methods or by static high-resolution structures, which complicate a detailed understanding of their dynamics. Here, we review the recent progress of single molecule Förster Resonance Energy Transfer (smFRET) in determining mechan ...[more]