Association between vesicoureteral reflux, urinary tract infection and antibiotics exposure in infancy and risk of childhood asthma.

ABSTRACT:

Background

The use of antibiotics for treating infection in childhood and their association with increased risk of asthma remain controversial. Infants diagnosed with vesicoureteral reflux (VUR) belong to a unique population who are administered antibiotics for a long time and are susceptible to recurrent UTI. It is interesting to study the risk of asthma in these infants with or without VUR.

Methods

Taiwanese children born between 2000 and 2007 were enrolled in population-based birth cohort study. Participants diagnosed with VUR and UTI within first year were classified into four groups (VUR, UTI, VUR and UTI, and control). We calculated follow-up person-years for each participant from the index date until the asthma diagnosis, their withdrawal from the insurance system (be

SUBMITTER: Hsu YL 

PROVIDER: S-EPMC8454937 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature