Chromatin accessibility profiling provides insights into larval cuticle color and adult longevity in butterflies.

ABSTRACT: Butterflies are diverse in virtually all aspects of their ontogeny, including morphology, life history, and behavior. However, the developmental regulatory mechanisms underlying the important phenotypic traits of butterflies at different developmental stages remain unknown. Here, we investigated the developmental regulatory profiles of butterflies based on transposase accessible chromatin sequencing (ATAC-seq) at three developmental stages in two representative species ( Papilio xuthus and Kallima inachus). Results indicated that 15%-47% of open chromatin peaks appeared in associated genes located 3 kb upstream (i.e., promoter region) of their transcription start site (TSS). Comparative analysis of the different developmental stages indicated that chromatin accessibility is a

SUBMITTER: Wan WT 

PROVIDER: S-EPMC8455473 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature