ColBuilder: A server to build collagen fibril models.
Ontology highlight
ABSTRACT:
SUBMITTER: Obarska-Kosinska A
PROVIDER: S-EPMC8456305 | biostudies-literature | 2021 Sep
REPOSITORIES: biostudies-literature
Publications
ColBuilder: A server to build collagen fibril models.
Obarska-Kosinska Agnieszka A Rennekamp Benedikt B Ünal Aysecan A Gräter Frauke F
Biophysical journal 20210713 17
Type I collagen is the main structural component of many tissues in the human body. It provides excellent mechanical properties to connective tissue and acts as a protein interaction hub. There is thus a wide interest in understanding the properties and diverse functions of type I collagen at the molecular level. A precondition is an atomistic collagen I structure as it occurs in native tissue. To this end, we built full-atom models of cross-linked collagen fibrils by integrating the low-resolut ...[more]
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