Ontology highlight
ABSTRACT:
SUBMITTER: Gaartman AE
PROVIDER: S-EPMC8456906 | biostudies-literature | 2021 Sep
REPOSITORIES: biostudies-literature
Gaartman Aafke E AE Sayedi Ajab K AK Gerritsma Jorn J JJ de Back Tim R TR van Tuijn Charlotte F CF Tang Man Wai MW Heijboer Harriët H de Heer Koen K Biemond Bart J BJ Nur Erfan E
British journal of haematology 20210715 5
Intravenous fluid therapy (IV-FT) is routinely used in the treatment of vaso-occlusive crises (VOCs), as dehydration possibly promotes and sustains erythrocyte sickling. Patients with sickle cell disease (SCD) are at risk of developing diastolic dysfunction and fluid overload due to IV-FT. However, data on the adverse effects of IV-FT for VOC is sparse. We aimed to evaluate the incidence and risk factors of fluid overload due to IV-FT in patients with SCD. Consecutive hospitalisations for VOC tr ...[more]