Psychiatric symptoms influence reward-seeking and loss-avoidance decision-making through common and distinct computational processes.

ABSTRACT:

Aim

Psychiatric symptoms are often accompanied by impairments in decision-making to attain rewards and avoid losses. However, due to the complex nature of mental disorders (e.g., high comorbidity), symptoms that are specifically associated with deficits in decision-making remain unidentified. Furthermore, the influence of psychiatric symptoms on computations underpinning reward-seeking and loss-avoidance decision-making remains elusive. Here, we aim to address these issues by leveraging a large-scale online experiment and computational modeling.

Methods

In the online experiment, we recruited 1900 non-diagnostic participants from the general population. They performed either a reward-seeking or loss-avoidance decision-making task, and subsequently completed questionnaires abo

SUBMITTER: Suzuki S 

PROVIDER: S-EPMC8457174 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature