Does low dose of etoricoxib play pre-emptive analgesic effect in third molar surgery? A randomized clinical trial.

ABSTRACT:

Background

How to prevent pain after the extraction of impacted teeth is a serious challenge for all patients. The purpose of this clinical trial was to investigate whether pre-emptive low dose of etoricoxib can reduce postoperative pain in patients undergoing third molars surgery.

Methods

Patients were randomised to receive etoricoxib 60 mg or placebo 30 min before surgery. Post-operative pain was recorded using a visual analogue scale during 24 h within the post-operative period. The total dose of ibuprofen rescue intake was recorded. Kaplan-Meier curves and log-rank analyses were used to evaluate the proportion of patients without rescue analgesic.

Results

Scores for the post-operative pain in the etoricoxib group were significantly lower than those in the placebo

SUBMITTER: Xie L 

PROVIDER: S-EPMC8459478 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature