Disentangling neocortical alpha/beta and hippocampal theta/gamma oscillations in human episodic memory formation.

ABSTRACT: To form an episodic memory, we must first process a vast amount of sensory information about the to-be-encoded event and then bind these sensory representations together to form a coherent memory trace. While these two cognitive capabilities are thought to have two distinct neural origins, with neocortical alpha/beta oscillations supporting information representation and hippocampal theta-gamma phase-amplitude coupling supporting mnemonic binding, evidence for a dissociation between these two neural markers is conspicuously absent. To address this, seventeen human participants completed an associative memory task that first involved processing information about three sequentially-presented stimuli, and then binding these stimuli together into a coherent memory trace, all the while undergoi

SUBMITTER: Griffiths BJ 

PROVIDER: S-EPMC8463840 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature