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Dural Sinus Arteriovenous Malformation in the Fetus. Case Report and Discussion of the Literature.

ABSTRACT: Sonographic findings of cerebral arteriovenous malformations in the fetus are uncommon and usually regard aneurysm of the Galen vein. Outcome of arteriovenous malformations is usually severe. We report a case of a fetus at 21 weeks' gestation with a rarer arteriovenous malformation, referred to us for echocardiography on account of a suspicious cardiomegaly at obstetrical scan. Upon examination, we found cardiomegaly, together with an associated moderate tricuspid regurgitation, however, there were no clear features of tricuspid dysplasia. Considering an unusually dilated superior vena cava, we found via color Doppler imaging a systodiastolic flow at Color Doppler progressing. Subsequent MRI of the central nervous system determined the localization in the sinus dura mater. Due to an already evident hemodynamic impact, the parents opted for the termination of the pregnancy. Autopsy confirmed a voluminous arteriovenous malformation of the transverse sinus of the dura mater, severe cardiomegaly, mainly of the ventricles, and hypoplasia of the lungs.

SUBMITTER: Fesslova V

PROVIDER: S-EPMC8464898 | biostudies-literature |

REPOSITORIES: biostudies-literature

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Intermixed arteriovenous malformation and hemangioblastoma: case report and literature review.

Project description:We report the third presentation of an intermixed arteriovenous malformation and hemangioblastoma. The rare occurrence of the diagnostic histologic features of both a neoplasm and vascular malformation in a single lesion is more common in gliomas, as angioglioma, and is termed an 'intermixed' lesion. We review the literature concerning the developmental biology of each lesion, and potential interplay in the formation of an intermixed vascular neoplasm and vascular malformation. The roles of cellular origin, genetic susceptibility, favourable microenvironment, altered local gene expression and key regulatory pathways are reviewed. Our review supports angiography and genetic profiling in intermixed lesions to inform management strategies. Consideration should be given to multimodality therapeutic interventions as required, including microsurgical resection, stereotactic radiosurgery and further research to exploit emerging molecular targets.

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| S-EPMC9282788 | biostudies-literature

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| S-EPMC7933698 | biostudies-literature

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| S-EPMC10496288 | biostudies-literature

Contrast-Enhanced Magnetic Resonance Imaging Suggested a Possibility of Transvenous Embolization in the Superior Petrosal Sinus Dural Arteriovenous Fistula: A Case Report.

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| S-EPMC10370784 | biostudies-literature

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| S-EPMC7317986 | biostudies-literature

Prenatal diagnosis of dural sinus malformation by two-dimensional combined with three-dimensional ultrasound: a case description.

Project description: Not available

| S-EPMC10784060 | biostudies-literature

Pulmonary arteriovenous malformation with unexplained cyanosis as the first presentation of hereditary haemorrhagic telangiectasia, case report, and literature review.

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| S-EPMC8343466 | biostudies-literature

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