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Dynamic Changes in Human Milk Oligosaccharides in Chinese Population: A Systematic Review and Meta-Analysis.


ABSTRACT: The aim of this systematic review was to summarize concentrations of human milk oligosaccharides (HMOs) in the Chinese population. We searched articles originally published in both Chinese and English. When compiling data, lactation was categorized into five stages. We found that 6'-sialyllactose, lacto-N-tetraose, and lacto-N-neotetraose decreased over lactation. Conversely, 3'-fucosyllactose increased over lactation. Our study represents the first systematic review to summarize HMO concentrations in Chinese population. Our findings not only provide data on HMO profiles in Chinese population but suggest future directions in the study of the metabolism of HMOs.

SUBMITTER: Zhou Y 

PROVIDER: S-EPMC8464947 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature

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Dynamic Changes in Human Milk Oligosaccharides in Chinese Population: A Systematic Review and Meta-Analysis.

Zhou Yalin Y   Sun Han H   Li Kaifeng K   Zheng Chengdong C   Ju Mengnan M   Lyu Ying Y   Zhao Runlong R   Wang Wenqing W   Zhang Wei W   Xu Yajun Y   Jiang Shilong S  

Nutrients 20210824 9


The aim of this systematic review was to summarize concentrations of human milk oligosaccharides (HMOs) in the Chinese population. We searched articles originally published in both Chinese and English. When compiling data, lactation was categorized into five stages. We found that 6'-sialyllactose, lacto-<i>N</i>-tetraose, and lacto-<i>N</i>-neotetraose decreased over lactation. Conversely, 3'-fucosyllactose increased over lactation. Our study represents the first systematic review to summarize H  ...[more]

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