Ontology highlight
ABSTRACT:
SUBMITTER: Prasad A
PROVIDER: S-EPMC8468151 | biostudies-literature | 2021 Sep
REPOSITORIES: biostudies-literature
Prasad Ankush A Manoharan Renuka Ramalingam RR Sedlářová Michaela M Pospíšil Pavel P
International journal of molecular sciences 20210915 18
Free radical-mediated activation of inflammatory macrophages remains ambiguous with its limitation to study within biological systems. U-937 and HL-60 cell lines serve as a well-defined model system known to differentiate into either macrophages or dendritic cells in response to various chemical stimuli linked with reactive oxygen species (ROS) production. Our present work utilizes phorbol 12-myristate-13-acetate (PMA) as a stimulant, and factors such as concentration and incubation time were co ...[more]