Ontology highlight
ABSTRACT:
SUBMITTER: Yamaguchi S
PROVIDER: S-EPMC8469729 | biostudies-literature | 2021 Sep
REPOSITORIES: biostudies-literature
Yamaguchi Shohei S Matsumoto Kento K Wang Wenhao W Nakamura Kozo K
Foods (Basel, Switzerland) 20210906 9
Acetylcholine (ACh) is a novel antihypertensive food component. Here, we demonstrate the differential effects of oral ACh on high and normal blood pressure in rats. Spontaneously hypertensive rats (SHRs) and Wistar-Kyoto (WKY) rats were administered ACh orally. The blood pressure and heart rate of SHRs were significantly lowered with ACh doses of 10<sup>-5</sup> and 10<sup>-3</sup> mol/kg body weight (b.w.), and the urinary catecholamine levels were significantly decreased with 10<sup>-3</sup> m ...[more]