Acute exercise decreases vaccine reactions following influenza vaccination among older adults.

ABSTRACT: Although valuable and effective in decreasing disease burden, influenza vaccination has low rates of efficacy, especially in those at most risk. Studies have shown that acute exercise can improve vaccine responses, most consistently with weaker antigens. Here we examined the effect of resistance exercise on the acute and longer-term responses to influenza vaccination among healthy older adults. Forty-six participants (47.8% male, mean 73.4 ± 6.6 years) were randomised to perform one 45-min moderate-intensity resistance exercise session or sit quietly prior to the receipt of influenza vaccination. Acute exercise reduced vaccine reactions but had no effect on either antibody responses or development of influenza-like symptoms during six months of follow-up. Psychosocial and behavioural chara

SUBMITTER: Bohn-Goldbaum E 

PROVIDER: S-EPMC8474530 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature