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Regioselective, Photocatalytic α-Functionalization of Amines.

ABSTRACT: Photocatalytic α-functionalization of amines provides a mild and atom-economical means to synthesize α-branched amines. Prior examples featured symmetrical or electronically biased substrates. Here we report a controllable α-functionalization of amines in which regioselectivity can be tuned with minor changes to the reaction conditions.

SUBMITTER: Leng L

PROVIDER: S-EPMC8475292 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature

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Regioselective, Photocatalytic α-Functionalization of Amines.

Leng Lingying L Fu Yue Y Liu Peng P Ready Joseph M JM

Journal of the American Chemical Society 20200630 28

Photocatalytic α-functionalization of amines provides a mild and atom-economical means to synthesize α-branched amines. Prior examples featured symmetrical or electronically biased substrates. Here we report a controllable α-functionalization of amines in which regioselectivity can be tuned with minor changes to the reaction conditions. ...[more]

PMID: 32573218

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